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郑国焱

副院长

1992、1995年于第一军医大学生物医学工程系获得学士和硕士学位。2002年于瑞士伯尔尼大学获得博士学位并留校工作。2005年在伯尔尼大学外科技术和生物力学研究所创立医学信息处理实验室并担任实验室主任。2010年获伯尔尼大学Privatedozent (PD)头衔,后于2015年担任伯尔尼大学副教授至2018年底。2019年1月1日加入上海交通大学。现任上海交通大学生物医学工程学院长聘教授,博士生导师,上海交通大学医疗机器人研究院影像导航介入中心主任。

2018年5月至6月获日本学术振兴会邀请任日本奈良先端科学技术大学院大学访问教授。

回国前,主持瑞士创新署创新项目3项,瑞士自然科学基金项目3项,日本瑞士科技合作项目1项,同时作为共同申请人获瑞士自然科学基金项目4项。已发表经同行评议的国际会议和杂志论文220多篇,Google引用3538次。在国际著名出版社Springer和Elsevier出版著作3部。已授权美国和欧洲发明专利8项。

2006和2018年获国际计算机辅助骨科年会最佳技术论文将,2018年获国际图像分析和识别大会Springer最佳论文奖,2018年获MICCAI脊柱成像中的计算方法和临床应用研讨会最佳论文奖,2017年获MICCAI医学成像中的机器学习研讨会最佳论文奖,2014年获国际计算机辅助放射学和外科学大会张贴论文奖,2012年获Journal of Laryngology and Otology杂志最佳基础论文奖,2009年获Ypsomed创新基金会研发大奖。2014获国际统计形状建模大会建模竞赛一等奖,2017年在国际婴儿大脑图像分割竞赛中的总共21个参赛队伍中获第三名。

 

研究方向

计算机辅助外科、多模影像分割、配准和重建、计算机辅助诊断、机器学习和深度学习

 

科研项目

瑞士自然科学基金项目:HEARTFUSION: Imaging-driven Patient-specific Cardiac Simulation

瑞士自然科学基金项目:Development and validation of a multi-modal image-based model generation method for non-invasive dynamic assessment of femoroacetabular impingement (FAI)

瑞士自然科学基金项目:Analysis and simulation of the distal forearm stability during pro-supination for improved surgical planning

瑞士创新署创新项目:3xPlan – Web-based planning and evaluation of orthopedic interventions

瑞士自然科学基金项目:Development of A Fully Automatic Lumbar Intervertebral Disc (IVD) MRI Segmentation Method and Its Applications in Spinal Diagnostic and Intervention Studies

日本瑞士科技合作项目:Development of a comprehensive system for assessment of sarcopenia, osteoporosis and joint dysfunction

瑞士创新署创新项目:iJoint: x-ray radiography based true 3D planning and evaluation system for total hip arthroplasty (THA)

瑞士自然科学基金项目:Patient-specific and pre-operative assessment of spine mechanical properties

瑞士自然科学基金项目:A statistical shape modeling platform for medical applications

 

代表性论文专著

Wang L, Nie D, Li G, Puybareau E, Dolz J, Zhang Q, Wang F, Xia J, Wu Z, Chen J, Thung KH, Bui TD, Shin J, Zeng G, Zheng G, Fonov VS, Doyle A, Xu Y, Moeskops P, Pluim JPW, Desrosiers C, Ayed IB, Sanroma G, Benkarim OM, Casamitjana A, Vilaplana V, Lin W, Li G, Shen D. Benchmark on Automatic 6-month-old Infant Brain Segmentation Algorithms: The iSeg-2017 Challenge. IEEE Trans Med Imaging, in press, 2019.

Yun HH, Murphy WS, Ward DM, Zheng G, Hayden B, Murphy SB. Effect of pelvic tilt and rotation on cup orientation in standing anteroposterior radiographs. Hip International, in press, 2019.

Soodmand E, Zheng G, Steens W, Bader R, Nolte L, Kluess D. Surgically Relevant Morphological Parameters of Proximal Human Femur: A Statistical Analysis Based on 3D Reconstruction of CT Data. Orthop Surg. 2019 Feb 27. doi: 10.1111/os.12416.

Damopoulos D, Lerch TD, Schmaranzer F, Tannast M, Chênes C, Zheng G*, Schmid J. Segmentation of the proximal femur in radial MR scans using a random forest classifier and deformable model registration. Int J Comput Assist Radiol Surg. 2019 Mar;14(3):545-561. doi: 10.1007/s11548-018-1899-z. Epub 2019 Jan 2。

Maier-Hein L, Eisenmann M, Reinke A, Onogur S, Stankovic M, Scholz P, Arbel T, Bogunovic H, Bradley AP, Carass A, Feldmann C, Frangi AF, Full PM, van Ginneken B, Hanbury A, Honauer K, Kozubek M, Landman BA, März K, Maier O, Maier-Hein K, Menze BH, Müller H, Neher PF, Niessen W, Rajpoot N, Sharp GC, Sirinukunwattana K, Speidel S, Stock C, Stoyanov D, Taha AA, van der Sommen F, Wang CW, Weber MA, Zheng G, Jannin P, Kopp-Schneider A. Why rankings of biomedical image analysis competitions should be interpreted with care. Nature Communications. Dec 6;9(1):5217. doi: 10.1038/s41467-018-07619-7。

N Kamiya, J Li, M Kume, H Fujita, D Shen and G Zheng*. Fully automatic segmentation of paraspinal muscles from 3D torso CT images via multi-scale iterative random forest classifications. International Journal of Computer Assisted Radiology and Surgery, 13(11):1697 – 1706, 2018

G Zheng. Gravity-assisted navigation system for total hip arthroplasty. Advances in experimental medicine and biology, 1093:181-191, 2018

L Liu, K Siebenrock, LP Nolte and G Zheng. Biomechanical Optimization-Based Planning of Periacetabular Osteotomy. Advances in experimental medicine and biology, 1093:157-168, 2018

L Liu, K Siebenrock, LP Nolte and G Zheng. Computer-Assisted Planning, Simulation, and Navigation System for Periacetabular Osteotomy. Advances in experimental medicine and biology, 1093:143-155, 2018

W Yu and G Zheng*. Atlas-Based 3D Intensity Volume Reconstruction from 2D Long Leg Standing X-Rays: Application to Hard and Soft Tissues in Lower Extremity. Advances in experimental medicine and biology, 1093:105-112, 2018

G Zheng, A Alcoltekin, B Thelen, LP Nolte. 3X-Knee: A Novel Technology for 3D Preoperative Planning and Postoperative Evaluation of TKA Based on 2D X-Rays. Advances in experimental medicine and biology, 1093:93-103, 2018

G Zeng and G Zheng*. Deep Learning-Based Automatic Segmentation of the Proximal Femur from MR Images. Advances in experimental medicine and biology, 1093:73-79, 2018

W Yu, W Liu, L Tan, S Zhang, G Zheng*. Multi-object Model-Based Multiatlas Segmentation Constrained Grid Cut for Automatic Segmentation of Lumbar Vertebrae from CT Images. Advances in experimental medicine and biology, 1093:65-71, 2018.

G Zheng and LP Nolte. Computer-Aided Orthopaedic Surgery: State-of-the-Art and Future Perspectives. Advances in experimental medicine and biology, 1093:1-20, 2018.

N Kamiya, J Li, M Kume, H Fujita, D Shen and G Zheng*. Fully automatic segmentation of paraspinal muscles from 3D torso CT images via multi-scale iterative random forest classifications. International Journal of Computer Assisted Radiology and Surgery, 13(11):1697 – 1706, 2018

X Li, Q Dou, H Chen, C-W Fu, X Qi, D.L. Belavy, G Armbrecht, D Felsenberg, G Zheng* and P-A Heng. 3D multi-scale FCN with random modality voxel dropout learning for intervertebral disc localization and segmentation from multi-modality MR images. Medical Image Analysis, 45:41-54, 2018

G Zheng, H Hommel, A Akcoltekin, B Thelen, J Stifter, G Peersman. A novel technology for 3D knee prosthesis planning and treatment evaluation using 2D X-ray radiographs: a clinical evaluation. International Journal of Computer Assisted Radiology and Surgery, 13:1151-1158, 2018

H Yun, WS Murphy, DM Ward, G Zheng, B Hayden, SB Murphy. Effect of Pelvic Tilt and Rotation on Cup Orientation in Both Supine and Standing Positions. The Journal of Arthroplasty, 33:1442-1448, 20

S Pflugi, R Vasireddy, T Lerch, TM Ecker, M Tannast, N Boemke, K. Siebenrock, G Zheng*. Augmented marker tracking for peri-acetabular osteotomy surgery. International Journal of Computer Assisted Radiology and Surgery, 13:291-304, 2018.

KJ Simson, CT Miller, J Ford, A Hahne, L Main, T Rantalainen, WP Teo, M Teychenne, D Connell, G Trudel, G Zheng, G Thickbroom, DL Belavy. Optimising conservative management of chronic low back pain: study protocol for a randomised controlled trial. Trial, 18:184(1-13), 2017. doi: 10.1186/s13063-017-1913-8

K. Karasawa, M. Oda, T. Kitasaka, K. Misawa, M. Fujiwara, C. Chu, G. Zheng, D. Rueckert, K. Mori. Multi-atlas pancreas segmentation: Atlas selection based on vessel structure. Medical Image Analysis, 39:18-28, 2017.

C Gökgöl, S Schumann, N Diehm, G Zheng and P Büchler. In-vivo quantification of femoro-popliteal artery deformations: percutaneous transluminal angioplasty vs. nitinol stent placement. Journal of Endovascular Therapy, 24:27-34, 2017.

S. Schumann, C. Gökgöl, N. Diehm, P. Büchler, G. Zheng. The effect of stent implantation on the deformations of the SFA and the popliteal artery: In-vivo 3D deformational analysis from 2D radiographs. Journal of Vascular and Interventional Radiology, 28:142-146, 2017.

W Yu, M Tannast, G Zheng*. Non-rigid free-form 2D-3D registration using a B-spline-based statistical deformation model. Pattern Recognition, 63:689-699, 2017.

G Zheng, C Chu, DL Belavy, B Ibragimov, R Korez, T Vrtovec, H Hutt, R Everson, J Meakin, IL Andrade, B Glocker, H Chen, Q Dou, PA Heng, C Wang, D Forsberg, A Neubert, J Fripp, M Urschler, D Stern, M Wimmer, AA Novikov, H Cheng, G Armbrecht, D Felsenberg, S Li. Evaluation and comparison of 3D intervertebral disc localization and segmentation methods for 3D T2 MR data: a grand challenge. Medical Image Analysis, 35:327-344, 2017.

S. Berger, C. Hasler,O. C.A. Grant, G. Zheng, S. Schumann, P. Büchler. A software program to measure the three-dimensional length of the spine from radiographic images: validation and reliability assessment for adolescent idiopathic scoliosis. Computer Methods and Programs in Biomedicine, 138:57-64, 2017.

W Yu, C Chu, M Tannast, and G Zheng*. Fully Automatic Reconstruction of Personalized 3D Volumes of the Proximal Femur from 2D X-ray Images. International Journal of Computer Assisted Radiology and Surgery, 11:1673-1685, 2016.

M Constantinescu, SL Lee, N Navkar, S Al-Rawas, J Abinahed, W Yu, G Zheng, A Al-Ansari, N Jomaah, P Landreau, GZ Yang. Constrained Statistical Modelling of Knee Flexion from Multi-Pose Magnetic Resonance Imaging. IEEE Transactions on Medical Imaging, 35:1686-1695, 2016.

M. Valenti, G. Ferrigno, D. Martina, W. Yu, G. Zheng, M.A. Shandiz, C. Anglin and E. De Momi. Gaussian Mixture Models based 2D-3D registration of bone shapes for orthopaedic surgery planning. Journal of Medical & Biological Engineering & Computing, 54:1727-1740, 2016。

J. M. Jennings, T.R. Randell, C. L. Green, G. Zheng, S.S. Wellman. Independent evaluation of a mechanical hip socket navigation system in total hip arthroplasty. The Journal of Arthroplasty, 31:658-661,2016.

M. Valenti, E. De Momi, W. Yu, G. Ferrigno, M.A. Shandiz, C. Anglin, G. Zheng. Fluoroscopy-based tracking of femoral kinematics with statistical shape models. International Journal of Computer Assisted Radiology and Surgery, 11:757-765, 2016.

L. Liu, G. Zheng, JD Bastian, MJ Keel, LP Nolte, KA Siebenrock, TM Ecker. Periacetabular osteotomy through the pararectus approach: technical feasibility and control of fragment mobility by a validated surgical navigation system in a cadaver environment. International Orthopaedics, 40:1389-1396, 2016.

S. Pflugi, L. Liu, T. M. Ecker, S. Schumann, J. Cullmann-Bastian, K. Siebenrock, G. Zheng. A cost-effective surgical navigation solution for periacetabular osteotomy (PAO) surgery. International Journal of Computer Assisted Radiology and Surgery, 11:271-280, 2016。

L. Liu, TM Ecker, S Schumann, KA Siebenrock, G. Zheng. Evaluation of Constant Thickness Cartilage Models vs. Patient Specific Cartilage Models for an Optimized Computer-Assisted Planning of Periacetabular Osteotomy. PLOS ONE, 11(1):e0146452, 2016; doi: 10.1371/journal.pone.0146452.

H. Cheng, L. Liu, W. Yu, H. Zhang, D. Luo, G. Zheng*. Comparison of 2.5D and 3D quantification of femoral head coverage in normal control subjects and patients with hip dysplasia. PLOS ONE, 10(11):e0143498, 2015; doi: 10.1371/journal.pone.0143498.

C. Chu, D.L. Belavy, G. Armbrecht, M. Bansmann, D. Felsenberg, G. Zheng*. Fully automatic localization and segmentation of 3D vertebral bodies from CT/MR images via a learning-based method. PLOS ONE, 10(11):e0143327, 2015; doi: 10.1371/journal.pone.0143327.

L. Liu, T. Ecker, L. Xie, S. Schumann, K. Siebenrock, G. Zheng*. Biomechanical Validation of Computer Assisted Planning of Periacetabular Osteotomy: A Preliminary Study based on Finite Element Analysis. Medical Engineering & Physics, 37:1169-1173, 2015.

S. Schumann, Y. Sato, Y. Nakanishi, F. Yokota, M. Takao, N. Sugano, G. Zheng. Cup implant planning based on 2-D/3-D radiographic pelvis reconstruction - first clinical results. IEEE Transactions on Biomedical Engineering, 62:2665-73, 2015.

C. Chu, J. Bai, X. Wu, G. Zheng*. Multi-Atlas Segmentation Constrained Graph Method for Accurate Segmentation of Hip CT Images. Medical Image Analysis, 26:173-184, 2015.

C. Chen, D. Belavy, W. Yu, C. Chu, G. Armbrecht, M. Bansmann, D. Felsenberg, G. Zheng*. Localization and segmentation of 3D intervertebral discs in MR images by data driven estimation. IEEE Transactions on Medical Imaging, 34:1719-1729, 2015。

C-W Wang, C-T Huang, M-C Hsieh, CH Li, SW Chang, WC Li, R Vandaele, R Marée, S Jodogne, P Geurts, C Chen, G Zheng, C Chu, H Mirzaalian, G Hamarneh, T Vrtovec, B Ibragimov. Evaluation and Comparison of Anatomical Landmark Detection Methods for Cephalometric X-Ray Images: A Grand Challenge. IEEE Transactions on Medical Imaging, 34:1890-1900, 2015.

C. Chen, R. Kojcev, D. Haschtmann,T. Fekete, L. Nolte, G. Zheng*. Ruler based automatic C-arm image stitching without overlapping constraint. Journal of Digital Imaging, 28:474-480, 2015

C. Chu, C. Chen, L. Liu, G. Zheng*. FACTS: Fully Automatic CT Segmentation of A Hip Joint. Annals of Biomedical Engineering, 43:1247-1259, 2015.

S. Berger, O. Marcello, S. Schumann, J. Schneider, D. Studer, C. Hasler, G. Zheng, P. Büchler. Patient-specific spinal stiffness in AIS: a preoperative and noninvasive method. European Spine Journal, 24:249-255, 2015.

M. Tannast, M.S. Hanke, G. Zheng, S.D. Steppacher, K.A. Siebenrock. What Are the Radiographic Reference Values for Acetabular Under- and Overcoverage? Clinical Orthopaedics and Related Research, 473:1234-1246, 2015.

W Xie, J. Franke, C Chen, PA Grützner, S Schumann, LP Nolte, G Zheng. A complete-pelvis segmentation framework for image-free total hip arthroplasty (THA): methodology and clinical study. The International Journal of Medical Robotics and Computer Assisted Surgery, 11:166-180, 2015.

M Tannast, S Fritsch, G Zheng, KA Siebenrock, SD Steppacher. Which Radiographic Hip Parameters Do Not Have to Be Corrected for Pelvic Rotation and Tilt? Clinical Orthopaedics and Related Research, 473:1255-1266, 2015.

P Büchler, ME de Oliveria, D Studer, S Schumann, G Zheng, J Schneider, CC Hasler. Axial suspension test to assess pre-operative spinal flexibility in patients with adolescent idiopathic scoliosis. European Spine Journal, 23:2619-2625, 2014.

B Craiovan, T Renkawitz, M Weber, J Grifka, L-P Nolte, G Zheng. Is the acetabular cup orientation after total hip arthroplasty on a two dimension or three dimension model accurate? International Orthopaedics, 38:2009-2015, 2014.

C Cheng, G Zheng. Fully automatic segmentation of AP pelvic X-rays via random forest regression with efficient feature selection and hierarchical sparse shape composition. Computer Vision and Image Understanding, 126:1-10, 2014.

S Schumann, B Thelen, S Ballestra, L-P Nolte, P Büchler, G Zheng*. X-ray image calibration and its application to clinical orthopedics. Medical Engineering & Physics, 36(7):968-74, 2014.

B. Helgason, S Gilchrist, O Ariza, JD Chak, G Zheng, RP Widmer, SJ Ferguson, P Guz, PA Cripton. Development of a balanced experimental-computational approach to understanding the mechanics of proximal femur fractures. Medical Engineering & Physics, 36(7):968-74, 2014.

W Xie, J Franke., C Chen, P Grützner, S Schumann, LP Nolte, G Zheng. Statistical model-based segmentation of the proximal femur in digital antero-posterior (AP) pelvic radiographs. International Journal of Computer Assisted Radiology and Surgery, 9:165-76, 2014.

C Chen, W Xie, J Franke, P Grutzner, LP Nolte, G Zheng*. Automatic X-ray landmark detection and shape segmentation via data-driven joint estimation of image displacements. Medical Image Analysis, 18:487-499, 2014.

S Schumann, L-P Nolte, G Zheng*. Comparison of partial least squares regression and principal component regression for pelvic shape prediction. Journal of Biomechanics, 46:197 – 199, 2013.

WS Murphy, G Klingenstein, SB Murphy, G Zheng. Pelvic tilt is minimally changed by total hip arthroplasty. Clinical Orthopaedics and Related Research, 471:417-421, 2013.

S. Schumann, L. Liu, M. Tannast, M. Bergmann, LP Nolte, G. Zheng*. An integrated system for 3D hip joint reconstruction from 2D X-rays: a preliminary validation study. Annals of Biomedical Engineering, 41:2077-2087, 2013.

S Schumann, L-P Nolte, and G Zheng. Determination of pelvic orientation from sparse ultrasound data for THA operated in the lateral position. The International Journal of Medical Robotics and Computer Assisted Surgery, 8: 107 – 113, 2012.

S Schumann, L-P Nolte, and G Zheng*. Compensation of sound speed deviations in 3-D B-mode ultrasound for intraoperative determination of the anterior pelvic plane. IEEE Transactions on Information Technology in Biomedicine (now renamed as IEEE Journal of Biomedical and Health Informatics), 16:88-97, 2012.

G Zheng, J von Recum, LP Nolte, PA Grützner, SD Steppacher, J Franke. Validation of a statistical shape model-based 2D/3D reconstruction method for determination of cup orientation after THA. International Journal of Computer Assisted Radiology and Surgery, 7:225-231, 2012.

ME de Oliveria, C-C Hasler, G Zheng, D Studer, J Schneider, P Büchler. A multi-criteria decision support for optimal instrumentation in scoliosis spine surgery. Structural and Multidisciplinary Optimization, 45:917-929, 2012.

J. Franke, G. Zheng, K. Wendl, P.a. Grützner, J. von Recum. Clinical experience with computer navigation in revision total hip arthroplasty. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 226:919-926, 2012.

G Zheng, Lutz-P Nolte, Stephen J Ferguson. Scaled, patient-specific 3D vertebral model reconstruction based on 2D lateral fluoroscopy. International Journal of Computer Assisted Radiology and Surgery, 6:351-66, 2011.

C Stieger, M Caversaccio, A Arnold, G Zheng, J Salzmann, D Widmer, N Gerber, M Thurner, C Nauer, Y Mussard, M Kompis, L P Nolte, R Häusler, S Weber. Development of an auditory implant manipulator (AIMAN) for minimally invasive surgical insertion of implantable hearing devices. The Journal of laryngology and otology, 125:262-270, 2011

G Zheng, X Zhang. Computer assisted determination of acetabular cup orientation using 2D-3D image registration. International Journal of Computer Assisted Radiology and Surgery, 5:437-447, 2010.

G Zheng, S Schumann, MA González Ballester. An integrated approach for reconstructing a surface model of the proximal femur from sparse input data and a multi-resolution point distribution model: an in vitro study. International Journal of Computer Assisted Radiology and Surgery, 5:99-107, 2010.

G Zheng. Assessing the accuracy factors in the determination of postoperative acetabular cup orientation using hybrid 2D-3D registration. Journal of Digital Imaging, 23:769-779, 2010.

G Zheng. Statistical shape model-based reconstruction of a scaled, patient-specific surface model of the pelvis from a single standard AP x-ray radiograph. Medical Physics, 37: 1424-1439, 2010.

G Zheng. Effective incorporating spatial information in a mutual information based 3D-2D registration of a CT volume to X-ray images. Computerized medical imaging and graphics, 34:553-562, 2010.

G Zheng. Statistically deformable 2D/3D registration for estimating post-operative cup orientation from a single standard AP X-ray radiograph. Annals of Biomedical Engineering, 38:2910-2927, 2010.

S Schumann, M Tannast, L-P Nolte, G Zheng. Validation of statistical shape model based reconstruction of the proximal femur--A morphology study. Medical Engineering & Physics 32:638-644, 2010

G Zheng, X Zhang, SD Steppacher, SB Murphy, KA Siebenrock, M Tannast. HipMatch: an object-oriented cross-platform program for accurate determination of cup orientation using 2D-3D registration of single standard X-ray radiograph and a CT volume. Computer Methods and Programs in Biomedicine, 95:236-248, 2009.

G Zheng, S Gollmer, S Schumann, X Dong, T Feilkas, MA González Ballester. A 2D/3D correspondence building method for reconstruction of a patient-specific 3D bone surface model using point distribution models and calibrated X-ray images. Medical Image Analysis, 13:883-899, 2009.

G Zheng, X Zhang. Robust automatic detection and removal of fiducial projections in fluoroscopy images: an integrated solution. Medical Engineering & Physics, 31:571-580, 2009.

X Dong, G Zheng*. Automatic extraction of proximal femur contours from calibrated X-ray images using 3D statistical models: an in vitro study. International Journal of Medical Robotics and Computer Assisted Surgery, 5:213-222, 2009.

G Zheng, S Schumann. 3D reconstruction of a patient-specific surface model of the proximal femur from calibrated x-ray radiographs: a validation study. Medical Physics, 36:1155-1166, 2009.

X Dong, G Zheng*. Matching parameterized shapes by nonparametric belief propagation. International Journal of Pattern Recognition and Artificial Intelligence, 23:209 – 246, 2009.

G Zheng, X Zhang. A novel parameter decomposition based optimization approach for automatic pose estimation of distal locking holes from single calibrated fluoroscopic image. Pattern Recognition Letters, 30:838-847, 2009.

R Thoranaghatte, J Garcia, M Caversaccio, D Widmer, MA Gonzalez Ballester, L-P Nolte, G Zheng. Landmark-based augmented reality system for paranasal and transnasal endoscopic surgeries. International Journal of Medical Robotics and Computer Assisted Surgery, 5:415-422, 2009.

SD Steppacher, M Tannast, G Zheng, X Zhang, J Kowal, SE Anderson, KA Siebenrock, SB Murphy. Validation of a new method for determination of cup orientation in THA. Journal of Orthopaedic Research, 27:1583-1588, 2009.

G Zheng, X Dong, PA Gruetzner. Reality-augmented virtual fluoroscopy for computer-assisted diaphyseal long bone fracture osteosynthesis: a novel technique and feasibility study results. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 222:101-115, 2008.

G Zheng, X Zhang, D Haschtmann, P Gedet, X Dong, L-Peter Nolte. A robust and accurate two-stage approach for automatic recovery of distal locking holes in computer-assisted intramedullary nailing of femoral shaft fractures. IEEE Transactions on Medical Imaging, 27:171-187, 2008.

M Rossol, D Gygax, J Andritzky-Waas, G Zheng, CJ Lischer, X Zhang, JA Auer. Comparison of computer assisted surgery with conventional technique for treatment of abaxial distal phalanx fractures in horses: an in vitro study. Veterinary Surgery, 37:32-42, 2008.

M Caversaccio, G Zheng, L - P Nolte. [Computer-aided surgery of the paranasal sinuses and the anterior skull base]. HNO, 56:376-378, 2008.

J García, R Thoranaghatte, G Marti, G Zheng, M Caversaccio, MA González Ballester. Calibration of a surgical microscope with automated zoom lenses using an active optical tracker. International Journal of Medical Robotics and Computer Assisted Surgery, 4:87-93, 2008.

M Tannast, S Mistry, SD Steppacher, S Reichenbach, F Langlotz, KA Siebenrock, G Zheng. Radiographic analysis of femoroacetabular impingement with Hip2Norm-reliable and validated. Journal of Orthopaedic Research, 26:1199-1205, 2008.

M Caversaccio, J Garcia Giraldez, R Thoranaghatte, G Zheng, P Eggli, L-P Nolte, MA Gonzalez Ballester. Augmented reality endoscopic system (ARES): preliminary results. Rhinology, 46:156-158, 2008.

G Zheng, X Dong, PAlfred Grutzner, L-P Nolte. Automated detection and segmentation of cylindrical fragments from calibrated C-arm images for long bone fracture reduction. Computer Methods and Programs in Biomedicine, 87:1-11, 2007.

B Maier, G Zheng, C Ploss, X Zhang, K Welle, L-P Nolte, I Marzi. A CT-free, intra-operative planning and navigation system for minimally invasive anterior spinal surgery - an accuracy study. Computer Aided Surgery, 12:233-241, 2007.

G Zheng, M Tannast, C Anderegg, K A Siebenrock, F Langlotz. Hip2Norm: an object-oriented cross-platform program for 3D analysis of hip joint morphology using 2D pelvic radiographs. Computer Methods and Programs in Biomedicine, 87:36-45, 2007.

KT Rajamani, MA Styner, H Talib, G Zheng, L-P Nolte, MA González Ballester. Statistical deformable bone models for robust 3D surface extrapolation from sparse data. Medical Image Analysis, 11:99-109, 2007.

G. Zheng, X. Zhang, D. Haschtmann, P. Gédet, F. Langlotz, L-P Nolte. Accurate and reliable pose recovery of distal locking holes in computer-assisted intra-medullary nailing of femoral shaft fractures: a preliminary study. Computer Aided Surgery, 12:138-151, 2007.

G Zheng, X Dong, KT Rajamani, X Zhang, M Styner, RU Thoranaghatte, L-P Nolte, MA González Ballester. Accurate and robust reconstruction of a surface model of the proximal femur from sparse-point data and a dense-point distribution model for surgical navigation. IEEE Transactions on Biomedical Engineering, 54:2109-2122, 2007.

S Hankemeier, T Hufner, G Wang, D Kendoff, J Zeichen, G Zheng, C Krettek. Navigated open-wedge high tibial osteotomy: advantages and disadvantages compared to the conventional technique in a cadaver study. Knee Surgery, Sports Traumatology, Arthroscopy, 14:917-921, 2006.

G Zheng, B Maier, C Ploss, I Marzi, L-P Nolte. Computer-assisted, fluoroscopy-based ventral spondylodesis of thoracolumbar fractures. Technology and Health Care, 14:109-122, 2006.

X Zhang, G Zheng*, F Langlotz, L-P Nolte. Assessment of spline-based 2D-3D registration for image-guided spine surgery. Minimally Invasive Therapy & Allied Technologies, 15:193-199, 2006.

M Tannast, G Zheng, C Anderegg, K Burckhardt, F Langlotz, R Ganz, KA Siebenrock. Tilt and rotation correction of acetabular version on pelvic radiographs. Clinical Orthopaedics and Related Research, 438:182-190, 2005。

PA Grützner, F Langlotz, G Zheng, J von Recum, C Keil, L-P Nolte, A Wentzensen, K Wendl. Computer-assisted LISS plate osteosynthesis of proximal tibia fractures: feasibility study and first clinical results. Computer Aided Surgery, 10:141-149, 2005.

S Hankemeier, T Hufner, G Wang, D Kendoff, G Zheng, M Richter, T Gosling, L-P Nolte, C Krettek. Navigated intraoperative analysis of lower limb alignment. Archives of Orthopaedic and Trauma Surgery, 125:531-535. 2005.

G Wang, G Zheng*, P Keppler, F Gebhard, A Staubli, U Mueller, D Schmucki, S Fluetsch, L-P Nolte. Implementation, accuracy evaluation, and preliminary clinical trial of a CT-free navigation system for high tibial opening wedge osteotomy. Computer Aided Surgery, 10:73-85, 2005.

S Sagbo, F Blochaou, F Langlotz, C Vangenot, L - P Nolte, G Zheng. New orthopaedic implant management tool for computer-assisted planning, navigation, and simulation: from implant CAD files to a standardized XML-based implant database. Computer Aided Surgery, 10:73-85, 2005.

RU Thoranaghatte, G Zheng, F Langlotz, L-P Nolte. Endoscope-based hybrid navigation system for minimally invasive ventral spine surgeries. Computer Aided Surgery, 10:351-356, 2005.

G Wang, G Zheng*, PA Gruetzner, U Mueller-Alsbach, J von Recum, A Staubli, L-P Nolte. A fluoroscopy-based surgical navigation system for high tibial osteotomy. Technology and Health Care, 13:469-483, 2005.

G Zheng, A Marx, U Langlotz, K-H Widmer, M Buttaro, L-P Nolte. A hybrid CT-free navigation system for total hip arthroplasty. Computer Aided Surgery, 7:129-145, 2002.

G Zheng, M Caversaccio, R Bächler, F Langlotz, L P Nolte, R Häusler. Frameless optical computer-aided tracking of a microscope for otorhinology and skull base surgery. JAMA Otolaryngology--Head & Neck Surgery, 127:1233-123, 2001.

B Huang, G Zheng, Z Xu, S Rao and S Wang. Application of image processing techniques in molecular imaging of cancer. Contrast Media & Molecular Imaging, 2017:2758749. doi: 10.1155/2017/2758749. eCollection 2017.

G. Zheng, L-P Nolte. Computer-assisted orthopaedic surgery: current state and future perspective. Frontiers in Surgery, 2:66. doi: 10.3389/fsurg.2015.00066., 2015.

G Zheng, S Li. Medical image computing in diagnosis and interventions of spinal diseases. Computerized Medical Imaging and Graphics, 45:99-101, 2015.

G Zheng, J Kowal, MA Gonzalez Ballester, M Caversaccio, L-P Nolte. Registration techniques for computer navigation. Current Orthopaedics 21:170 – 179, 2007.

D Schmucki, F Gebhard, PA Grützner, T Hüfner, F Langlotz, G Zheng. Computer aided reduction and imaging. Injury, 35 Suppl 1:S-A96-104, 2004.

PA Grützner, G Zheng, U Langlotz, J von Recum, L-P Nolte, A Wentzensen, K-H Widmer, K Wendl. C-arm based navigation in total hip arthroplasty-background and clinical experience. Injury, 35 Suppl 1:S-A90-95, 2004.

P Keppler, F Gebhard, PA Grützner, G Wang, G Zheng, T Hüfner, S Hankemeier, L-P Nolte. Computer aided high tibial open wedge osteotomy. Injury, 35 Suppl 1:S-A68-78, 2004.

Wentzensen, G Zheng, B Vock, U Langlotz, J Korber, L-P Nolte, PA Grützner. Image-based hip navigation. International Orthopaedics, 27 Suppl 1: S43-S46, 2003.

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